- Abstract:
-
This study investigated the influence of pre-treatment proliferation characteristics, assessed by Ki-67 staining, in patients treated in the CHART trial of accelerated radiotherapy in head and neck cancer. Histological material from 402 patients was collected and stained for the presence and pattern of Ki-67 staining. Locoregional control and overall survival were the main clinical endpoints. Increasing Ki-67 positivity was associated with decreasing differentiation (P < 0.001) and increas...
Expand abstract - Publisher copy:
- 10.1016/j.ejca.2005.10.022
-
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- Journal:
- European journal of cancer (Oxford, England : 1990)
- Volume:
- 42
- Issue:
- 3
- Pages:
- 363-371
- Publication date:
- 2006-02-05
- DOI:
- EISSN:
-
1879-0852
- ISSN:
-
0959-8049
- URN:
-
uuid:73425d71-5d04-41bc-abff-33173ee035c8
- Source identifiers:
-
283422
- Local pid:
- pubs:283422
- Copyright date:
- 2006
Journal article
Pre-treatment proliferation and the outcome of conventional and accelerated radiotherapy.
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