- Abstract:
-
We have created a global map of the effects of polymorphism on gene expression in 400 children from families recruited through a proband with asthma. We genotyped 408,273 SNPs and identified expression quantitative trait loci from measurements of 54,675 transcripts representing 20,599 genes in Epstein-Barr virus-transformed lymphoblastoid cell lines. We found that 15,084 transcripts (28%) representing 6,660 genes had narrow-sense heritabilities (H2) > 0.3. We executed genome-wide associati...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/ng2109
-
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- Journal:
- Nature genetics
- Volume:
- 39
- Issue:
- 10
- Pages:
- 1202-1207
- Publication date:
- 2007-10-05
- DOI:
- EISSN:
-
1546-1718
- ISSN:
-
1061-4036
- URN:
-
uuid:733d99a9-210b-43fb-beb2-799d160857b9
- Source identifiers:
-
66720
- Local pid:
- pubs:66720
- Language:
- English
- Keywords:
- Copyright date:
- 2007
Journal article
A genome-wide association study of global gene expression.
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