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Effect of electroconvulsive therapy on neural response to affective pictures: a randomised, sham-controlled fMRI study

Abstract:

Electroconvulsive therapy (ECT) is the most effective treatment for severe depression but its neurocognitive mechanisms are unclear. This randomized, sham-controlled functional magnetic resonance imaging (fMRI) study explored the effects of a single ECT on neural response to affective pictures. Twenty-seven patients with major depressive disorder were randomized to a single active ECT (N = 15) or sham (N = 12) session in a double-blind, parallel-group design. On the following day, patients un...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1016/j.euroneuro.2018.05.013

Authors


Miskowiak, KW More by this author
Macoveanu, J More by this author
Jørgensen, MB More by this author
Støttrup, MM More by this author
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Publisher:
Elsevier Publisher's website
Journal:
European Neuropsychopharmacology Journal website
Volume:
28
Issue:
8
Pages:
915-924
Publication date:
2018-06-08
Acceptance date:
2018-05-21
DOI:
ISSN:
0924-977X
Pubs id:
pubs:853588
URN:
uri:7323e52b-f760-4486-9b44-fbf4d91d542d
UUID:
uuid:7323e52b-f760-4486-9b44-fbf4d91d542d
Local pid:
pubs:853588

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