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How does the humoral response to HIV-2 infection differ from HIV-1 and can this explain the distinct natural history of infection with these two human retroviruses?

Abstract:

A substantial proportion of people infected with HIV-2, the second causative agent of acquired immune deficiency syndrome (AIDS), behave as long-term non-progressors (LTNP) and are able to control the infection more effectively than most HIV-1-infected patients. A better understanding of the differences in the natural history of HIV-1 and HIV-2 infection, and how these relate to the relative immunogenicity and evolution of the two virus strains, could provide important insights into the mecha...

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Publisher copy:
10.1016/j.imlet.2014.10.028

Authors


Publisher:
Elsevier
Journal:
Immunology letters
Volume:
163
Issue:
1
Pages:
69-75
Publication date:
2014-11-05
DOI:
EISSN:
1879-0542
ISSN:
0165-2478
URN:
uuid:73070d45-5336-4ca7-8356-8cba1668cd80
Source identifiers:
492533
Local pid:
pubs:492533

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