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PRImary care Streptococcal Management (PRISM) study: in vitro study, diagnostic cohorts and a pragmatic adaptive randomised controlled trial with nested qualitative study and cost-effectiveness study.

Abstract:

BACKGROUND: Antibiotics are still prescribed to most patients attending primary care with acute sore throat, despite evidence that there is modest benefit overall from antibiotics. Targeting antibiotics using either clinical scoring methods or rapid antigen detection tests (RADTs) could help. However, there is debate about which groups of streptococci are important (particularly Lancefield groups C and G), and uncertainty about the variables that most clearly predict the presence of streptoco...

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Publication status:
Published

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Publisher copy:
10.3310/hta18060

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-International
Williamson, I More by this author
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Journal:
Health technology assessment (Winchester, England)
Volume:
18
Issue:
6
Pages:
vii-101
Publication date:
2014-01-05
DOI:
EISSN:
2046-4924
ISSN:
1366-5278
URN:
uuid:72f5eb71-3b27-4b9f-a417-4ebf8c7c3fb5
Source identifiers:
447926
Local pid:
pubs:447926

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