- Abstract:
-
Immunological synapses are organized cell-cell junctions between T lymphocytes and APCs composed of an adhesion ring, the peripheral supramolecular activation cluster (pSMAC), and a central T cell receptor cluster, the central supramolecular activation cluster (cSMAC). In CD8(+) cytotoxic T lymphocytes, the immunological synapse is thought to facilitate specific killing by confining cytotoxic agents to the synaptic cleft. We have investigated the interaction of human CTLs and helper T cells w...
Expand abstract - Publisher copy:
- 10.1172/jci19337
-
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- Journal:
- The Journal of clinical investigation
- Volume:
- 113
- Issue:
- 1
- Pages:
- 49-57
- Publication date:
- 2004-01-05
- DOI:
- EISSN:
-
1558-8238
- ISSN:
-
0021-9738
- URN:
-
uuid:72dee3de-b808-4f20-80de-463b0f880562
- Source identifiers:
-
482636
- Local pid:
- pubs:482636
- Copyright date:
- 2004
Journal article
Cytotoxic T lymphocytes form an antigen-independent ring junction.
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