Immunological synapses are organized cell-cell junctions between T lymphocytes and APCs composed of an adhesion ring, the peripheral supramolecular activation cluster (pSMAC), and a central T cell receptor cluster, the central supramolecular activation cluster (cSMAC). In CD8(+) cytotoxic T lymphocytes, the immunological synapse is thought to facilitate specific killing by confining cytotoxic agents to the synaptic cleft. We have investigated the interaction of human CTLs and helper T cells w...Expand abstract
- Publisher copy:
- Copyright date:
Cytotoxic T lymphocytes form an antigen-independent ring junction.
If you are the owner of this record, you can report an update to it here: Report update to this record