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Thesis

Enantioselective synthesis and reactivity of benzylic fluorides

Abstract:

Benzylic fluorides are attractive target molecules for medicinal chemistry, agrochemicals and materials chemistry. The enantioselective synthesis of benzylic fluorides is challenging and few general methods exist. This thesis describes several approaches to the synthesis of benzylic fluoride targets, including enantioselective processes.

Chapter 1: Reviews the properties, uses and synthetic approaches to fluorinated molecules, with a particular focus on benzylic fluorides and enantio...

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Institution:
University of Oxford
Research group:
Gouverneur
Oxford college:
Pembroke College
Department:
Mathematical,Physical & Life Sciences Division - Chemistry - Organic Chemistry

Contributors

Role:
Supervisor
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Funding agency for:
George R. Blessley
Publication date:
2013
Type of award:
DPhil
Level of award:
Doctoral
URN:
uuid:72cd3684-a339-453c-a9e8-c976ff731a0e
Local pid:
ora:8075

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