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Journal article

TLR2 is expressed on activated T cells as a costimulatory receptor.

Abstract:

Toll is the founder of a group of pattern recognition receptors that play a critical role in the innate immunity in Drosophila. At least 10 distinct Toll-like receptors (TLRs), recognizing pathogen-associated molecular patterns, have now been identified in humans. Most investigations on TLRs have focused on cells of the innate system. We report here that naïve human T cells expressed high levels of cell-surface TLR2 after activation by anti-T cell receptor antibody and IFN-alpha. Activated ce...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.0400171101

Authors


Komai-Koma, M More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-CTU
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
101
Issue:
9
Pages:
3029-3034
Publication date:
2004-03-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:72c88828-1728-47ce-90ef-73b02c01b233
Source identifiers:
5755
Local pid:
pubs:5755

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