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Journal article

Radiation-induced apoptosis varies among individuals and is modified by sex and age.

Abstract:

PURPOSE: Although there are considerable data on mechanisms of radiation-induced apoptosis in vitro and in animal models, little is known about functional variation in these pathways in humans. We sought to develop a tractable system to evaluate this. MATERIALS AND METHODS: Peripheral blood mononuclear cells were isolated from 90 healthy volunteers, divided into two aliquots, one irradiated with a 5 Gy dose and the other sham-treated (0 Gy), and assessed for damage-induced apoptosis after 24 ...

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Publication status:
Published

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Journal:
International journal of radiation biology
Volume:
90
Issue:
10
Pages:
903-908
Publication date:
2014-10-05
DOI:
EISSN:
1362-3095
ISSN:
0955-3002
URN:
uuid:72b1d14c-604b-497f-97cd-66197f381b97
Source identifiers:
469137
Local pid:
pubs:469137

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