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Journal article

Persistent high frequencies of varicella-zoster virus ORF4 protein-specific CD4+ T cells after primary infection.

Abstract:

Open reading frame 4 (ORF4) of varicella-zoster virus (VZV) encodes an immediate-early protein that is believed to be important for viral infectivity and establishing latency. Evidence suggests that VZV-specific T cells are crucial in the control of viral replication, but there are no data addressing the existence of potential ORF4 protein-specific CD4+ T cells. We tested the hypothesis that VZV ORF4 protein-specific CD4+ T cells could be identified and characterized within the peripheral blo...

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Publication status:
Published

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Publisher copy:
10.1128/jvi.00564-06

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Primary Care Health Sciences, PHC-CTU
Role:
Author
Journal:
Journal of virology
Volume:
80
Issue:
19
Pages:
9772-9778
Publication date:
2006-10-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:729acc37-6866-4d29-ad32-d92746239a9f
Source identifiers:
28028
Local pid:
pubs:28028

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