- Abstract:
-
Open reading frame 4 (ORF4) of varicella-zoster virus (VZV) encodes an immediate-early protein that is believed to be important for viral infectivity and establishing latency. Evidence suggests that VZV-specific T cells are crucial in the control of viral replication, but there are no data addressing the existence of potential ORF4 protein-specific CD4+ T cells. We tested the hypothesis that VZV ORF4 protein-specific CD4+ T cells could be identified and characterized within the peripheral blo...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1128/jvi.00564-06
-
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- Journal:
- Journal of virology
- Volume:
- 80
- Issue:
- 19
- Pages:
- 9772-9778
- Publication date:
- 2006-10-05
- DOI:
- EISSN:
-
1098-5514
- ISSN:
-
0022-538X
- URN:
-
uuid:729acc37-6866-4d29-ad32-d92746239a9f
- Source identifiers:
-
28028
- Local pid:
- pubs:28028
- Copyright date:
- 2006
Journal article
Persistent high frequencies of varicella-zoster virus ORF4 protein-specific CD4+ T cells after primary infection.
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