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Separation and identification of rat skeletal muscle proteins using two-dimensional gel electrophoresis and mass spectrometry.

Abstract:

Skeletal muscle plays a major role in whole body protein metabolism, and changes in the rates of synthesis and degradation of proteins are likely to lead to characteristic changes in the amounts of different proteins in muscle under various physiological and pathological conditions. This paper demonstrates the feasibility of a proteomic approach to analyzing the protein composition of skeletal muscle. We report here the initial establishment of two-dimensional gel electrophoresis (2-D PAGE) r...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Welson, SY More by this author
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Journal:
Proteomics
Volume:
1
Issue:
3
Pages:
424-434
Publication date:
2001-03-05
DOI:
EISSN:
1615-9861
ISSN:
1615-9853
URN:
uuid:72827ce1-1978-414c-8301-e0e95dc1b857
Source identifiers:
230171
Local pid:
pubs:230171

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