Journal article
What makes a good genetic association study?
- Abstract:
-
Genetic association studies are central to efforts to identify and characterise genomic variants underlying susceptibility to multifactorial disease. However, obtaining robust replication of initial association findings has proved difficult. Much of this inconsistency can be attributed to inadequacies in study design, implementation, and interpretation--inadequately powered sample groups are a major concern. Several additional factors affect the quality of any given association study, with ap...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/s0140-6736(05)67531-9
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Bibliographic Details
- Journal:
- Lancet
- Volume:
- 366
- Issue:
- 9493
- Pages:
- 1315-1323
- Publication date:
- 2005-10-01
- DOI:
- EISSN:
-
1474-547X
- ISSN:
-
0140-6736
- Source identifiers:
-
16191
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:16191
- UUID:
-
uuid:7245062e-96c0-4c91-9905-1643afa82179
- Local pid:
- pubs:16191
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2005
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