HLA restriction of cell-mediated lysis of influenza virus-infected human cells.
- MURINE T lymphocytes that mediate the lysis of virus-infected cells show specificity both for the viral cell surface antigens and for the H-2K or D antigens of the major histo-compatibility complex1-8. The cytotoxic T lymphocytes and the target cell must share H-2K or D products. The experiments reported here demonstrate that there is a similar requirement for partial HLA identity between human cytotoxic lymphocytes and influenza virus-infected target cells. © 1977 Nature Publishing Group.
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