- Abstract:
-
OBJECTIVE: The purpose of this work was to develop a rapid 3-D, variable flip angle (VFA) method for measurement of hyperpolarized (3)He T(1) which accounts for the effects of radiofrequency (RF) pulses without the need for additional flip angle information. MATERIALS AND METHODS: The 3-D, VFA method was validated in vitro over a range of oxygen partial pressures ranging from 0.04 to 0.52 atm. The approach was also tested in vivo in five healthy rats as a function of increasing number of was...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1007/s10334-009-0181-3
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- Journal:
- Magma (New York, N.Y.)
- Volume:
- 22
- Issue:
- 5
- Pages:
- 309-318
- Publication date:
- 2009-10-05
- DOI:
- EISSN:
-
1352-8661
- ISSN:
-
0968-5243
- URN:
-
uuid:72198c84-964e-4a3f-8e33-d549d22cc770
- Source identifiers:
-
441914
- Local pid:
- pubs:441914
- Copyright date:
- 2009
Journal article
Rapid 3-D mapping of hyperpolarized 3He spin-lattice relaxation times using variable flip angle gradient echo imaging with application to alveolar oxygen partial pressure measurement in rat lungs.
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