Journal article
Optimal sequencing strategies for surveying molecular genetic diversity.
- Abstract:
-
Two commonly used measures of genetic diversity for intraspecies DNA sequence data are based, respectively, on the number of segregating sites, and on the average number of pairwise nucleotide differences. Expressions are derived for their variance in the presence of intragenic recombination for a panmictic population of fixed size that is at neutral equilibrium at the region sequenced. We show that, in contrast to the slow decrease in variance with increasing sample size, if the recombinatio...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Genetics
- Volume:
- 144
- Issue:
- 3
- Pages:
- 1247-1262
- Publication date:
- 1996-11-01
- EISSN:
-
1943-2631
- ISSN:
-
0016-6731
- Source identifiers:
-
69406
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:69406
- UUID:
-
uuid:7208169d-350a-4ac1-bc5f-848ec4a1f65a
- Local pid:
- pubs:69406
- Deposit date:
- 2012-12-19
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- Copyright date:
- 1996
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