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Journal article

Low dose melatonin improves sleep in healthy middle-aged subjects.

Abstract:

We studied the effects of single evening doses of melatonin (0.3 mg and 1.0 mg orally) on polysomnographically measured sleep in 15 healthy middle-aged volunteers, using a placebo-controlled, double-blind, cross-over design. Compared to placebo, the 1.0 mg dose of melatonin significantly increased Actual Sleep Time, Sleep Efficiency, non-REM Sleep and REM Sleep Latency. These data are consistent with the hypothesis that low dose melatonin has hypnotic effects in humans. It is possible that ad...

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Publication status:
Published

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Publisher copy:
10.1007/bf02246354

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
Journal:
Psychopharmacology
Volume:
126
Issue:
2
Pages:
179-181
Publication date:
1996-07-05
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
URN:
uuid:71d6b64d-149f-4960-91c7-377df16c1030
Source identifiers:
186063
Local pid:
pubs:186063

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