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What you see is not what you get: implications of the brevity of antibody responses to malaria antigens and transmission heterogeneity in longitudinal studies of malaria immunity.

Abstract:

BACKGROUND: A major handicap in developing a malaria vaccine is the difficulty in pinpointing the immune responses that protect against malaria. The protective efficacy of natural or vaccine-induced immune responses against malaria is normally assessed by relating the level of the responses in an individual at the beginning of a follow-up period and the individual's experience of malaria infection or disease during the follow-up. This approach has identified a number of important responses a...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1475-2875-8-242

Authors


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Institution:
University of Oxford
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Author
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Institution:
University of Oxford
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
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Funding agency for:
Kinyanjui, S
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Funding agency for:
Osier, F
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Funding agency for:
Bull, P
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Funding agency for:
Marsh, K
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Publisher:
BioMed Central Publisher's website
Journal:
Malaria Journal Journal website
Volume:
8
Issue:
1
Article number:
242
Publication date:
2009-01-01
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
Source identifiers:
41442
Language:
English
Keywords:
UUID:
uuid:71b53ea1-0601-4d24-a29f-1b71d7e3b2dd
Local pid:
pubs:41442
Deposit date:
2012-12-19

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