Improved kidney graft function after preservation using a novel hypothermic machine perfusion device.

Journal article

OBJECTIVE: To study graft function and ischemia/reperfusion injury of porcine kidneys after preservation with the new Groningen Machine Perfusion (GMP) system versus static cold storage (CS). INTRODUCTION: The increasing proportion of marginal and nonheart beating donors necessitates better preservation methods to maintain adequate graft viability. Hypothermic machine preservation (HMP) is a promising alternative to static CS. We have therefore developed and tested an HMP device, which is po...

Expand abstract

Authors: Maathuis, M; Manekeller, S; van der Plaats, A; Leuvenink, H; 't Hart, N

• Publication status: Published
• Journal: Annals of surgery
• Volume: 246
• Issue: 6
• Pages: 982-988
• Publication date: 2007-12-01
• DOI: 10.1097/sla.0b013e31815c4019
• EISSN: 1528-1140
• ISSN: 0003-4932
• Language: English
• Keywords: Microcirculation; Renal Circulation; Kidney Cortex; Biopsy; Kidney Transplantation; Equipment Design; Recovery of Function; Organ Preservation; Reperfusion Injury; Animals; Hypothermia, Induced; Disease Models, Animal; Treatment Outcome; Transplantation, Autologous; Female; Swine; Perfusion