- Abstract:
-
Circulating levels of adiponectin, an adipocyte-secreted protein associated with cardiovascular and metabolic risk, are highly heritable. To gain insights into the biology that regulates adiponectin levels, we performed an exome array meta-analysis of 265,780 genetic variants in 67,739 individuals of European, Hispanic, African American, and East Asian ancestry. We identified 20 loci associated with adiponectin, including 11 that had been reported previously (p < 2 × 10-7). Comparison of e...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Files:
-
-
(pdf)
- Publisher copy:
- 10.1016/j.ajhg.2019.05.002
-
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- Publisher:
- Elsevier Publisher's website
- Journal:
- American Journal of Human Genetics Journal website
- Volume:
- 105
- Issue:
- 1
- Pages:
- 15-28
- Publication date:
- 2019-08-06
- Acceptance date:
- 2019-04-30
- DOI:
- EISSN:
-
1537-6605
- ISSN:
-
0002-9297
- Pmid:
-
31178129
- Pubs id:
-
pubs:1011612
- UUID:
-
uuid:719a9e4b-6e57-4ac5-a8fa-3184f8724c43
- Source identifiers:
-
1011612
- Local pid:
- pubs:1011612
- Language:
- English
- Keywords:
- Copyright holder:
- American Society of Human Genetics
- Copyright date:
- 2019
- Rights statement:
- © 2019 American Society of Human Genetics.
- Notes:
- This is the accepted manuscript version of the article. The final version is available from Elsevier at: https://doi.org/10.1016/j.ajhg.2019.05.002. A correction to this article is available at: https://doi.org/10.1016/j.ajhg.2019.08.001
Journal article
Exome-derived adiponectin-associated variants implicate obesity and lipid biology
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