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Protein structure controls the processing of the N-linked oligosaccharides and glycosylphosphatidylinositol glycans of variant surface glycoproteins expressed in bloodstream form Trypanosoma brucei

Abstract:

The variant surface glycoproteins (VSGs) of Trypanosoma brucei are a family of homodimeric glycoproteins that adopt similar shapes. An individual trypanosome expresses one VSG at a time in the form of a dense protective mono­layer on the plasma membrane. VSG genes are expressed from one of several polycistronic transcription units (expression sites) that contain several expression site associated genes. We used a transformed trypanosome clone expressing two different VSGs (VSG121 and VSG221) ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/glycob/10.3.243

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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
Publisher:
Oxford University Press Publisher's website
Journal:
Glycobiology Journal website
Volume:
10
Issue:
3
Pages:
243-249
Publication date:
2000-01-01
DOI:
EISSN:
1460-2423
ISSN:
0959-6658
URN:
uuid:717db61e-b670-4a8f-94cf-39a889b6b8fb
Source identifiers:
100696
Local pid:
pubs:100696

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