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Autoantibodies to the islet cell antigen SOX-13 are associated with duration but not type of diabetes.

Abstract:

AIMS: The autoantigen SOX-13 of the SRY-related high mobility group box is a low-frequency reactant in sera from patients with Type 1 diabetes. We further investigated the potential diagnostic role of anti-SOX-13, and in particular its ability to distinguish Type 1 from Type 2 diabetes, in two large, well-characterized cohorts. METHODS: SOX-13 autoantibody status was ascertained using a radioimmunoprecipitation assay in (i) a random sample of 546 participants in an Australian community-based ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Mackay, IR More by this author
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Journal:
Diabetic medicine : a journal of the British Diabetic Association
Volume:
20
Issue:
3
Pages:
198-204
Publication date:
2003-03-05
DOI:
EISSN:
1464-5491
ISSN:
0742-3071
URN:
uuid:71718d11-594e-4a2a-88a8-052e4ee58667
Source identifiers:
22411
Local pid:
pubs:22411

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