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Journal article

Joint estimation of cardiac toxicity and recurrence risks after comprehensive nodal photon vs. proton therapy for breast cancer

Abstract:

Purpose

To perform joint estimation of the risk of recurrence caused by inadequate radiation dose coverage of lymph node targets and the risk of cardiac toxicity caused by radiation exposure to the heart. Delivered photons plans are compared to realistic proton plans thereby providing evidence-based estimates of the heterogeneity of treatment effects in consecutive cases for the two radiation modalities.

Methods and Materials

Forty-one patients referred for post-l...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/j.ijrobp.2016.12.008

Authors


Maraldo, MV More by this author
More by this author
Department:
Oxford, MSD, Nuffield Department of Population Health, Clinical Trial Service Unit
Pedersen, AN More by this author
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Kirsten and Freddy Johansen’s Foundation More from this funder
Publisher:
Elsevier Publisher's website
Journal:
International Journal of Radiation Oncology*Biology*Physics Journal website
Volume:
97
Issue:
4
Pages:
754–761
Publication date:
2016-12-05
Acceptance date:
2016-12-02
DOI:
EISSN:
1879-355X
ISSN:
0360-3016
Pubs id:
pubs:682410
URN:
uri:716c41e3-eba5-4a4e-9156-27d53af6c2b3
UUID:
uuid:716c41e3-eba5-4a4e-9156-27d53af6c2b3
Local pid:
pubs:682410

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