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Journal article

A novel gene expression profile in lymphatics associated with tumor growth and nodal metastasis.

Abstract:

Invasion of lymphatic vessels is a key step in the metastasis of primary tumors to draining lymph nodes. Although the process is enhanced by tumor lymphangiogenesis, it is unclear whether this is a consequence of increased lymphatic vessel number, altered lymphatic vessel properties, or both. Here we have addressed the question by comparing the RNA profiles of primary lymphatic endothelial cells (LEC) isolated from the vasculature of normal tissue and from highly metastatic T-241/vascular end...

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Publication status:
Published

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Authors


Clasper, S More by this author
Royston, D More by this author
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Journal:
Cancer research
Volume:
68
Issue:
18
Pages:
7293-7303
Publication date:
2008-09-05
DOI:
EISSN:
1538-7445
ISSN:
0008-5472
URN:
uuid:714d95ed-19fd-48eb-be6b-aa7c8e9c5068
Source identifiers:
102712
Local pid:
pubs:102712

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