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Immunity against heterosubtypic influenza virus induced by adenovirus and MVA expressing nucleoprotein and matrix protein-1.

Abstract:

Alternate prime/boost vaccination regimens employing recombinant replication-deficient adenovirus or MVA, expressing Influenza A virus nucleoprotein and matrix protein 1, induced antigen-specific T cell responses in intradermally (ID) vaccinated mice; with the strongest responses resulting from Ad/MVA immunization. In BALB/C mice the immunodominant response was shifted from the previously identified immunodominant epitope to a novel epitope when the antigen was derived from A/Panama/2007/1999...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/srep01443

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Jenner Institute
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Jenner Institute
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Jenner Institute
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Jenner Institute
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Publisher:
Nature Publishing Group Publisher's website
Journal:
Scientific reports Journal website
Volume:
3
Pages:
1443
Publication date:
2013
DOI:
EISSN:
2045-2322
ISSN:
2045-2322
URN:
uuid:712c29d4-f868-4072-b3c5-c4fb5b6705e4
Source identifiers:
387768
Local pid:
pubs:387768

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