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Regulation of the Pcl7-Pho85 cyclin-cdk complex by Pho81.

Abstract:

Saccharomyces cerevisiae strains lacking a functional Pho85 cyclin-dependent kinase (cdk) exhibit a complex phenotype, including deregulation of phosphatase genes controlled by the transcription factor Pho4, slow growth on rich media, failure to grow using galactose, lactate or glycerol as a carbon source and hyperaccumulation of glycogen. The ability of Pho85 to regulate the transcription factor Pho4 is mediated by its association the Pho80 cyclin. Some other regulatory functions of the Pho8...

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Publication status:
Published

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Authors


O'Regan, S More by this author
Moreau, JL More by this author
Johnson, AL More by this author
Johnston, LH More by this author
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Journal:
Molecular microbiology
Volume:
38
Issue:
2
Pages:
411-422
Publication date:
2000-10-05
DOI:
EISSN:
1365-2958
ISSN:
0950-382X
URN:
uuid:710a030b-d4e0-451e-b0d4-a1a85e8679bc
Source identifiers:
92909
Local pid:
pubs:92909

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