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Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization

Abstract:

Impulse propagation in biological tissues is known to be modulated by structural heterogeneity. In cardiac muscle, improved understanding on how this heterogeneity influences electrical spread is key to advancing our interpretation of dispersion of repolarization. We propose fractional diffusion models as a novel mathematical description of structurally heterogeneous excitable media, as a means of representing the modulation of the total electric field by the secondary electrical sources a...

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Publisher copy:
10.1098/rsif.2014.0352

Authors


A. Bueno−Orovio More by this author
B. Rodriguez More by this author
K. Burrage More by this author
Journal:
Journal of the Royal Society Interface
Volume:
11
Pages:
20140352
Publication date:
2014
DOI:
URN:
uuid:70f50a9c-d2b1-458e-bf3e-6f7952d0a24b
Local pid:
cs:8798

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