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Serum fasting cortisol in relation to bone, and the role of genetic variations in the glucocorticoid receptor.

Abstract:

OBJECTIVE: To examine the relationship between endogenous cortisol and bone, and the role of genetic variations in the glucocorticoid receptor (GR). DESIGN AND PATIENTS: The Longitudinal Ageing Study Amsterdam (LASA), a population-based cohort study in older men and women. MEASUREMENTS: Serum fasting cortisol was assessed by competitive immunoassay (n = 1214); bone mineral density (BMD) by dual X-ray absorptiometry (DXA) (n = 502); broadband ultrasound attenuation (BUA) by ultrasound (n = 120...

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Publication status:
Published

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Authors


van Schoor, NM More by this author
Dennison, E More by this author
Uitterlinden, AG More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Journal:
Clinical endocrinology
Volume:
67
Issue:
6
Pages:
871-878
Publication date:
2007-12-05
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
URN:
uuid:70c13a43-64a6-43ee-b182-99218cf2411e
Source identifiers:
125696
Local pid:
pubs:125696

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