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Journal article

Synthesis and evaluation of a 99mTechnetium labeled chitin-binding protein as potential specific radioligand for the detection of fungal infections in mice.

Abstract:

AIM: Radiopharmaceuticals can be used to exploit differences between microorganisms in order to distinguish fungal from bacterial infection. Chitin, abundant in the cell wall of fungi, is not present in mammalian or bacterial cells and therefore represents a highly specific target to localize fungal infection. In this study, we have examined the potential of chitin-binding protein (CBP21) from Serratia marcescens as a specific radiotracer for the detection of invasive fungal infections. METHO...

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Publication status:
Published

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Authors


Eijsink, VG More by this author
Vaaje-Kolstad, G More by this author
Vandenbulcke, K More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
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Journal:
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..
Volume:
50
Issue:
3
Pages:
155-166
Publication date:
2006-09-05
EISSN:
1827-1936
ISSN:
1824-4785
URN:
uuid:7007f008-3d4d-47ac-8f55-8b37ceb4fecb
Source identifiers:
262715
Local pid:
pubs:262715

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