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Interplay between recombination, cell division and chromosome structure during chromosome dimer resolution in Escherichia coli.

Abstract:

Chromosome dimers form in bacteria by recombination between circular chromosomes. Resolution of dimers is a highly integrated process involving recombination between dif sites catalysed by the XerCD recombinase, cell division and the integrity of the division septum-associated FtsK protein and the presence of dif inside a restricted region of the chromosome terminus, the dif activity zone (DAZ). We analyse here how these phenomena collaborate. We show that (i) both inter- and intrachromosomal...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
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Journal:
Molecular microbiology
Volume:
39
Issue:
4
Pages:
904-913
Publication date:
2001-02-05
DOI:
EISSN:
1365-2958
ISSN:
0950-382X
URN:
uuid:6feb163d-dac6-4e88-bf01-4ea42779cf49
Source identifiers:
100043
Local pid:
pubs:100043

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