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Journal article

Renal cell carcinoma: translational aspects of metabolism and therapeutic consequences.

Abstract:

The heterogeneity of renal cell carcinoma (RCC) poses a challenge for designing clinically applicable diagnostic and screening investigations, predictive and prognostic biomarkers, and targeted molecular therapies. Hereditary RCC syndromes harbor specific driver gene mutations, and their discoveries have provided unequivocal insight into the pathogenomic landscape of RCCs. These observed genetic aberrations correspond to a diverse range of dysplastic metabolic processes, including mutations i...

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Publication status:
Published

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Publisher copy:
10.1038/ki.2013.245

Authors


Maxwell, PH More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Journal:
Kidney international
Volume:
84
Issue:
4
Pages:
667-681
Publication date:
2013-10-05
DOI:
EISSN:
1523-1755
ISSN:
0085-2538
URN:
uuid:6fe46895-de2a-4975-bcf8-8a777fc14384
Source identifiers:
410277
Local pid:
pubs:410277

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