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A combined three-dimensional in vitro-in silico approach to modelling bubble dynamics in decompression sickness.

Abstract:

The growth of bubbles within the body is widely believed to be the cause of decompression sickness (DCS). Dive computer algorithms that aim to prevent DCS by mathematically modelling bubble dynamics and tissue gas kinetics are challenging to validate. This is due to lack of understanding regarding the mechanism(s) leading from bubble formation to DCS. In this work, a biomimetic in vitro tissue phantom and a three-dimensional computational model, comprising a hyperelastic strain-energy density...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1098/rsif.2017.0653

Authors


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ORCID:
0000-0003-3769-3392
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Institution:
University of Oxford
Division:
MPLS Division
Department:
Engineering Science
Oxford college:
St Catherines College
ORCID:
0000-0003-3371-5929
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ORCID:
0000-0002-9781-665X
Publisher:
Royal Society Publisher's website
Journal:
Journal of the Royal Society, Interface Journal website
Volume:
14
Issue:
137
Pages:
20170653
Publication date:
2017-12-05
Acceptance date:
2017-11-29
DOI:
EISSN:
1742-5689
ISSN:
1742-5662
Pubs id:
pubs:813020
URN:
uri:6fb49508-116e-4f26-873c-e5bc5e6ae3ad
UUID:
uuid:6fb49508-116e-4f26-873c-e5bc5e6ae3ad
Local pid:
pubs:813020

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