Journal article
Canonical Notch signaling is dispensible for adult steady-state and stress myelo-erythropoiesis
- Abstract:
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While an essential role for canonical Notch signaling in generation of hematopoietic stem cells in the embryo and in thymic T cell development is well established, its role in adult bone marrow (BM) myelopoiesis remains unclear. Some studies, analyzing myeloid progenitors in adult mice with inhibited Notch signaling, implicated distinct roles of canonical Notch signaling in regulation of progenitors for the megakaryocyte, erythroid and granulocyte-macrophage cell lineages. However, these stud...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
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(Accepted manuscript, pdf, 1.1MB)
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- Publisher copy:
- 10.1182/blood-2017-06-788505
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Authors
Funding
EUFPEuroSyStem Integrated project
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Swedish Research Council
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+ Science and Technology Foundation, Ministry of Education and Science
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Grant:
SFRH/BD/36816/2007
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Bibliographic Details
- Publisher:
- American Society of Hematology Publisher's website
- Journal:
- Blood Journal website
- Volume:
- 131
- Issue:
- 15
- Pages:
- 1712-1719
- Publication date:
- 2018-01-16
- Acceptance date:
- 2018-01-10
- DOI:
- EISSN:
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1528-0020
- ISSN:
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0006-4971
- Pmid:
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29339402
- Source identifiers:
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821321
Item Description
- Language:
- English
- Pubs id:
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pubs:821321
- UUID:
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uuid:6fa5cf63-6f03-40b0-b629-11803f1ee8a4
- Local pid:
- pubs:821321
- Deposit date:
- 2018-03-01
Terms of use
- Copyright holder:
- American Society of Hematology
- Copyright date:
- 2018
- Notes:
- Copyright © 2018 by The American Society of Hematology. This is the accepted manuscript version of the article. The final version is available online from American Society of Hematology at: https://doi.org/10.1182/blood-2017-06-788505
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