Clinical application of comprehensive chromosomal screening at the blastocyst stage.

Journal article

OBJECTIVE: To evaluate a new strategy for comprehensive chromosome screening at the blastocyst stage. DESIGN: Clinical research study. SETTING: An IVF clinic and a specialist preimplantation genetic diagnosis laboratory. PATIENT(S): Forty-five infertile couples participated in the study. The mean maternal age was 37.7 years, and most couples had at least one previous unsuccessful IVF treatment cycle (mean 2.4). INTERVENTION(S): This study used a novel chromosome screening approach, combining...

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Authors: Schoolcraft, W; Fragouli, E; Stevens, J; Munne, S; Katz-Jaffe, MG

• Publication status: Published
• Journal: Fertility and sterility
• Volume: 94
• Issue: 5
• Pages: 1700-1706
• Publication date: 2010-10-01
• DOI: 10.1016/j.fertnstert.2009.10.015
• EISSN: 1556-5653
• ISSN: 0015-0282
• Language: English
• Keywords: Preimplantation Diagnosis; Embryo Transfer; Fertilization in Vitro; Genetic Testing; Blastocyst; Pregnancy Rate; Chromosomes; Humans; Aneuploidy; Adult; Female; Male; Outcome Assessment (Health Care); Pregnancy