- Abstract:
-
The repair of dermal tissue is a complex process of interconnected phenomena, where cellular, chemical and mechanical aspects all play a role, both in an autocrine and in a paracrine fashion. Recent experimental results have shown that transforming growth factor -β (TGFβ) and tissue mechanics play roles in regulating cell proliferation, differentiation and the production of extracellular materials. We have developed a 1D mathematical model that considers the interaction between the cellular, ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.jtbi.2010.12.011
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- Journal:
- Journal of theoretical biology
- Volume:
- 272
- Issue:
- 1
- Pages:
- 145-159
- Publication date:
- 2011-03-05
- DOI:
- EISSN:
-
1095-8541
- ISSN:
-
0022-5193
- URN:
-
uuid:6f8a008b-d468-4217-b065-f69108088082
- Source identifiers:
-
149576
- Local pid:
- pubs:149576
- Language:
- English
- Keywords:
- Copyright date:
- 2011
Journal article
A two-compartment mechanochemical model of the roles of transforming growth factor β and tissue tension in dermal wound healing.
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