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Children's Oxygen Administration Strategies Trial (COAST):  A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia

Abstract:
Background: In Africa, the clinical syndrome of pneumonia remains the leading cause of morbidity and mortality in children in the post-neonatal period. This represents a significant burden on in-patient services. The targeted use of oxygen and simple, non-invasive methods of respiratory support may be a highly cost-effective means of improving outcome, but the optimal oxygen saturation threshold that results in benefit and the best strategy for delivery are yet to be tested i... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Department:
EXTERNAL
Role:
Author
ORCID:
0000-0002-0007-0645
More by this author
Role:
Author
ORCID:
0000-0002-5757-609X
Publisher:
F1000Research
Journal:
Wellcome Open Research More from this journal
Volume:
2
Article number:
100
Place of publication:
England
Publication date:
2018-01-09
Acceptance date:
2018-01-16
DOI:
EISSN:
2398-502X
Pmid:
29383331
Language:
English
Keywords:
Pubs id:
928771
Local pid:
pubs:928771
Deposit date:
2021-05-21

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