Journal article
Scavenger receptor A: a new route for adenovirus 5.
- Abstract:
-
Adenoviruses are common pathogens associated with respiratory diseases, gastrointestinal illnesses and/or conjunctivitis. Currently, this virus is used as a vector in gene therapy trials. The promise of viral gene therapy applications is substantially reduced because the virus is cleared by liver macrophages upon systemic administration. The mechanism underlying adenoviral tropism to and degradation in macrophages is poorly understood. We identified a new adenoviral receptor, the scavenger re...
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- Publication status:
- Published
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- Publisher copy:
- 10.1021/mp8000974
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Bibliographic Details
- Journal:
- Molecular pharmaceutics
- Volume:
- 6
- Issue:
- 2
- Pages:
- 366-374
- Publication date:
- 2009-01-01
- DOI:
- EISSN:
-
1543-8392
- ISSN:
-
1543-8384
- Source identifiers:
-
6018
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:6018
- UUID:
-
uuid:6f53ce65-3606-4dcf-82bf-2925dc788d0b
- Local pid:
- pubs:6018
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2009
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