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Journal article

The expression of gelatinase A (MMP-2) is required for normal development of zebrafish embryos.

Abstract:

Gelatinase A, also called matrix metalloproteinase 2 (MMP-2), belongs to the matrix metalloproteinase (MMP) family. MMP-2 cleaves type IV collagen, denatured collagen (gelatin), and other extracellular matrix (ECM) components. MMP-2 has been reported to be involved in a number of biological and pathological processes, but previous studies have not indicated that its expression is essential for early embryogenesis. In the current study, we have utilized zebrafish as a developmental model to st...

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Publication status:
Published

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Publisher copy:
10.1007/s00427-003-0346-4

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
Development genes and evolution
Volume:
213
Issue:
9
Pages:
456-463
Publication date:
2003-09-05
DOI:
EISSN:
1432-041X
ISSN:
0949-944X
URN:
uuid:6f3dbecd-9eb8-4575-9686-0a5d7d8a640f
Source identifiers:
226976
Local pid:
pubs:226976

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