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Thesis

Eutherian-specific homeobox genes in the preimplantation embryo; function, evolution, and applications.

Abstract:

This thesis explores the evolution, function, and possible applications of a group of lineage-specific genes known as the Eutherian Totipotent Cell Homeobox (ETCHbox) genes. The ETCHbox genes duplicated from a highly conserved vertebrate eye-specific homeobox gene called Cone-rod homeobox (CRX) in the lineage leading to eutherian mammals. The ETCHbox genes are unusual in many respects. Firstly, they are eutherian-specific, meaning that they are only present in the genomes of one grou...

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Division:
MPLS
Department:
Zoology
Role:
Author

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Role:
Supervisor
Biotechnology & Biological Sciences Research Council More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Subjects:
UUID:
uuid:6f3daa7c-872e-4534-a5d1-d78cdf73d51d
Deposit date:
2019-12-11

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