Journal article
Structural changes during ion channel gating
- Abstract:
-
Ion channels are generally multi-subunit complexes, with the ion conduction pathway formed at the subunit interface. In moving between the closed and open states, three structurally distinct channels, represented by the recently determined structures of a mechanosensitive, ligand-gated and K(+) selective channel, all move transmembrane helices away from the central ion conduction pathway. In all three cases, this results in the displacement of a hydrophobic gate from the ion conduction pathwa...
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Bibliographic Details
- Journal:
- Trends in Neurosciences
- Volume:
- 27
- Issue:
- 6
- Pages:
- 298-302
- Publication date:
- 2004-01-01
- ISSN:
-
0166-2236
Item Description
- Language:
- English
- Subjects:
- UUID:
-
uuid:6f2a80a9-61ac-4f04-a605-628a3a50b59b
- Local pid:
- SGC:15165732
- Deposit date:
- 2011-08-18
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- Copyright date:
- 2004
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