- Abstract:
-
BACKGROUND: There are reasons to expect an association with Alzheimer's disease (AD) within the HLA region. The HLA-B and C genes have, however, been relatively understudied. A geographically specific association with HLA-B7 and HLA-Cw*0702 had been suggested by our previous, small study. METHODS: We studied the HLA-B and C alleles in 196 cases of 'definite' or 'probable' AD and 199 elderly controls of the OPTIMA cohort, the largest full study of these alleles in AD to date. RESULTS: We repl...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1186/1742-2094-3-33
-
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- Journal:
- Journal of neuroinflammation
- Volume:
- 3
- Pages:
- 33
- Publication date:
- 2006
- DOI:
- EISSN:
-
1742-2094
- ISSN:
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1742-2094
- URN:
-
uuid:6f25af63-0851-4c88-b9b4-ad5c2ecd5aba
- Source identifiers:
-
140541
- Local pid:
- pubs:140541
- Language:
- English
- Copyright date:
- 2006
Journal article
Replication of the association of HLA-B7 with Alzheimer's disease: a role for homozygosity?
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