Journal article icon

Journal article

Heritability and coefficient of genetic variation analyses of phenotypic traits provide strong basis for high-resolution QTL mapping in the Collaborative Cross mouse genetic reference population

Abstract:

Most biological traits of human importance are complex in nature; their manifestation controlled by the cumulative effect of many genetic factors interacting with one another and with the individual's life history. Because of this, mouse genetic reference populations (GRPs) consisting of collections of inbred lines or recombinant inbred lines (RIL) derived from crosses between inbred lines are of particular value in analysis of complex traits, since massive amounts of data can be accumulated ...

Expand abstract

Actions


Access Document


Publisher copy:
10.1007/s00335-014-9503-5

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Publisher:
Springer New York LLC
Journal:
Mammalian Genome
Volume:
25
Issue:
3-4
Pages:
109-119
Publication date:
2014-01-01
DOI:
EISSN:
1432-1777
ISSN:
0938-8990
Language:
English
Pubs id:
pubs:459692
UUID:
uuid:6f1b7fd6-f6ad-4343-bbd1-8cbeae5957d3
Local pid:
pubs:459692
Source identifiers:
459692
Deposit date:
2014-05-13

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP