Journal article
Reactive oxygen species and cyclooxygenase 2-derived thromboxane A2 reduce angiotensin II type 2 receptor vasorelaxation in diabetic rat resistance arteries.
- Abstract:
-
Angiotensin II has a key role in the control of resistance artery tone and local blood flow. Angiotensin II possesses 2 main receptors. Although angiotensin II type 1 receptor is well known and is involved in the vasoconstrictor and growth properties of angiotensin II, the role of the angiotensin II type 2 receptor (AT2R) remains much less understood. Although AT2R stimulation induces vasodilatation in normotensive rats, it induces vasoconstriction in pathological conditions involving oxidati...
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- Publication status:
- Published
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- Publisher copy:
- 10.1161/hypertensionaha.109.140236
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Bibliographic Details
- Journal:
- Hypertension
- Volume:
- 55
- Issue:
- 2
- Pages:
- 339-344
- Publication date:
- 2010-02-01
- DOI:
- EISSN:
-
1524-4563
- ISSN:
-
0194-911X
- Source identifiers:
-
164556
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:164556
- UUID:
-
uuid:6f0fd0c6-ecf0-43e0-9566-f369e1887d43
- Local pid:
- pubs:164556
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2010
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