Brain activation during an auditory 'oddball task' in schizophrenia measured by single photon emission tomography.

Journal article

BACKGROUND: The study examines the effect of an auditory discrimination task on regional brain perfusion in schizophrenic patients. METHODS: Twenty patients were examined with single photon emission tomography (SPET), both resting and performing an auditory two-tone 'oddball' discrimination task. Statistical parametric mapping (SPM'95) was used to identify local activation effects and correlations between event related potential measures and regional perfusion. RESULTS: Compared with rest, pa...

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Authors: Shajahan, P; Glabus, M; Blackwood, D; Ebmeier, K

• Journal: Psychological medicine
• Volume: 27
• Issue: 3
• Pages: 587-594
• Publication date: 1997-05-01
• DOI: 10.1017/s0033291797004728
• EISSN: 1469-8978
• ISSN: 0033-2917
• Language: English
• Keywords: Event-Related Potentials, P300; Schizophrenia; Discrimination (Psychology); Analysis of Variance; Cerebrovascular Circulation; Brain; Humans; Adult; Female; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon; Auditory Perception; Male