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Quantifying previous SARS-CoV-2 infection through mixture modelling of antibody levels

Abstract:

As countries decide on vaccination strategies and how to ease movement restrictions, estimating the proportion of the population previously infected with SARS-CoV-2 is important for predicting the future burden of COVID-19. This proportion is usually estimated from serosurvey data in two steps: first the proportion above a threshold antibody level is calculated, then the crude estimate is adjusted using external estimates of sensitivity and specificity. A drawback of this approach is that the...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1038/s41467-021-26452-z

Authors


Publisher:
Springer Nature Publisher's website
Journal:
Nature Communications Journal website
Volume:
12
Article number:
6196
Publication date:
2021-10-26
Acceptance date:
2021-09-17
DOI:
ISSN:
2041-1723
Language:
English
Keywords:
Pubs id:
1187584
Local pid:
pubs:1187584
Deposit date:
2021-07-27

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