Journal article
Evidence for post-translational processing of vascular endothelial (VE)-cadherin in brain tumors: towards a candidate biomarker
- Abstract:
-
Vessel abnormalities are among the most important features in malignant glioma. Vascular endothelial (VE)-cadherin is of major importance for vascular integrity. Upon cytokine challenge, VE-cadherin structural modifications have been described including tyrosine phosphorylation and cleavage. The goal of this study was to examine whether these events occurred in human glioma vessels. We demonstrated that VE-cadherin is highly expressed in human glioma tissue and tyrosine phosphorylated at site...
Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS ONE Journal website
- Volume:
- 8
- Issue:
- 12
- Pages:
- ARTN e80056
- Publication date:
- 2013-12-16
- Acceptance date:
- 2013-09-30
- DOI:
- EISSN:
-
1932-6203
Item Description
- Language:
- English
- Keywords:
- UUID:
-
uuid:6eec84e7-ddcb-477b-8748-696e2ca1a5d0
- Local pid:
- pubs:491253
- Source identifiers:
-
491253
- Deposit date:
- 2014-12-10
Terms of use
- Copyright holder:
- Vilgrain et al
- Copyright date:
- 2013
- Notes:
- Copyright: © 2013 Vilgrain et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record