Declining malaria transmission differentially impacts the maintenance of humoral immunity to Plasmodium falciparum in children
We investigated the poorly understood impact of declining malaria transmission on maintenance of antibodies to Plasmodium falciparum merozoite antigens and infected erythrocytes (IEs), including functional immunity.
In a 3-year longitudinal cohort of 300 Kenyan children, antibodies to different AMA1 and MSP2 alleles of merozoites, IE surface antigens, and antibody functional activities were quantified.
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- Peer review status:
- Peer reviewed
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- Copyright holder:
- Mugyenyi, CK et al.
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- © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved.
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