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Oxetane amino acids: synthesis of tetrameric and hexameric carbopeptoids derived from L-ribo 4-(aminomethyl)-oxetan-2-carboxylic acid

Abstract:
The synthesis of methyl 2,4-anhydro-5-azido-3-O-benzyl-5-deoxy-l-ribonate, a δ-2,4-cis-oxetane-azido ester scaffold derived from l-arabinose, is reported. Iterative coupling methods were utilised to form homo-oligomers up to the hexamer in order to investigate the secondary structural preferences of these systems. © 2008 Elsevier Ltd. All rights reserved.
Publication status:
Published

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Authors


Lopez-Ortega, B More by this author
Jenkinson, SF More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Journal:
TETRAHEDRON-ASYMMETRY
Volume:
19
Issue:
8
Pages:
976-983
Publication date:
2008-05-01
DOI:
EISSN:
1362-511X
ISSN:
0957-4166
URN:
uuid:6ed6e559-fccc-4730-88d4-ee9563ab9e1f
Source identifiers:
40745
Local pid:
pubs:40745
Language:
English

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