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Homocysteine-lowering trials for prevention of vascular disease: protocol for a collaborative meta-analysis.

Abstract:

BACKGROUND: Elevated plasma total homocysteine is a risk factor for cardiovascular disease (CVD), but the randomized trials of dietary supplementation with B-vitamins to lower homocysteine have not yet provided clear evidence of benefit on vascular risk. METHODS: Cumulative meta-analysis of all randomized trials assessing the effects of lowering homocysteine levels with B-vitamins on risk of CVD. RESULTS: An individual patient data meta-analysis of all randomized trials of the effects on vasc...

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Publication status:
Published

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Publisher copy:
10.1515/cclm.2007.346

Authors


Armitage, J More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Trial Service Unit
Collins, R More by this author
Journal:
Clinical chemistry and laboratory medicine : CCLM / FESCC
Volume:
45
Issue:
12
Pages:
1575-1581
Publication date:
2007
DOI:
EISSN:
1437-4331
ISSN:
1434-6621
URN:
uuid:6ecbd46f-5247-45e1-97ad-f34e70bdde14
Source identifiers:
34125
Local pid:
pubs:34125

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