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A model of the interaction between autoregulation and neural activation in the brain.

Abstract:

In this paper a model is proposed that predicts the response of the cerebral vasculature to changes in arterial blood pressure, arterial CO2 concentration and neural stimulation. Cerebral blood flow (CBF) is assumed to be controlled through changes in arterial compliance, and hence arterial resistance and volume, through three feedback mechanisms, which act in a linear additive manner, based on CBF, arterial CO2 and neural stimulus. Together with arterial, capillary and venous compartments, a...

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Publication status:
Published

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Publisher copy:
10.1016/j.mbs.2006.08.006

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Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
Role:
Author
Journal:
Mathematical biosciences
Volume:
204
Issue:
2
Pages:
260-281
Publication date:
2006-12-05
DOI:
EISSN:
1879-3134
ISSN:
0025-5564
URN:
uuid:6ec9f48a-3b7e-474c-b46b-de9dec277066
Source identifiers:
64372
Local pid:
pubs:64372

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