- Abstract:
-
Rapamycin has long been considered an immunosuppressive agent due to its antiproliferative effects on immune cells, and is currently used as a component of antirejection regimens in transplantation. Despite the large number of mechanistic and clinical studies investigating the impact of rapamycin on cell-mediated immunity, several paradoxes concerning rapamycin immunobiology remain. In particular, emerging evidence suggests that under certain circumstances rapamycin can exert immunostimulator...
Expand abstract - Publisher copy:
- 10.1111/j.1600-6143.2011.03473.x
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- Journal:
- American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
- Volume:
- 11
- Issue:
- 4
- Pages:
- 654-659
- Publication date:
- 2011-04-05
- DOI:
- EISSN:
-
1600-6143
- ISSN:
-
1600-6135
- URN:
-
uuid:6ec935f0-4327-48ed-8c36-264fa8a9d4a9
- Source identifiers:
-
400761
- Local pid:
- pubs:400761
- Language:
- English
- Keywords:
- Copyright date:
- 2011
Journal article
Paradoxical aspects of rapamycin immunobiology in transplantation.
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