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Journal article

Paradoxical aspects of rapamycin immunobiology in transplantation.

Abstract:

Rapamycin has long been considered an immunosuppressive agent due to its antiproliferative effects on immune cells, and is currently used as a component of antirejection regimens in transplantation. Despite the large number of mechanistic and clinical studies investigating the impact of rapamycin on cell-mediated immunity, several paradoxes concerning rapamycin immunobiology remain. In particular, emerging evidence suggests that under certain circumstances rapamycin can exert immunostimulator...

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Authors


Ferrer, IR More by this author
Journal:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Volume:
11
Issue:
4
Pages:
654-659
Publication date:
2011-04-05
DOI:
EISSN:
1600-6143
ISSN:
1600-6135
URN:
uuid:6ec935f0-4327-48ed-8c36-264fa8a9d4a9
Source identifiers:
400761
Local pid:
pubs:400761

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